Programa de Pós-Graduação em Farmacologia e Química Medicinal
ARTIGOS EM PERIÓDICOS
2023 (em atualização)
Aquino, Gabriel A. S.; Silva-Jr, Floriano P.; Ferreira, Sabrina B.. Ethyl Diazoacetate. SyOpen, v. 7, p. 110-113, 2023.
Araujo-Lima, Carlos F.; de Cassia, Carvalho, Rita de C. C.; Rosario, Sandra L.; Leite, Debora I.; Aguiar, Anna C. C.; Santos, Lizandra V. de S.; de Araujo, Julianna S.; Salomão, Kelly; Kaiser, Carlos R.; Krettli, Antoniana U.; Bastos, Monica M.; Aiub, Claudia A. F.; Soeiro, Maria de N. C.; Boechat, Nubia; Felzenszwalb, I.. Antiplasmodial, Trypanocidal, and Genotoxicity In Vitro Assessment of New Hybrid α,α-Difluorophenylacetamide-statin Derivatives. Pharmaceutical, v. 16, p. 782, 2023.
Araujo-Lima, Carlos F.; Carvalho, Rita de C. C.; Peres, Raiza B.; Fiuza, Ludmila F. de A.; Galvão, Bárbara V. D.; Castelo-Branco, Frederico S.; Bastos, Mônica M.; Boechat, Nubia; Felzenszwalb, I.; Soeiro, Maria de N. C.. In silico and in vitro assessment of anti-Trypanosoma cruzi efficacy, genotoxicity and pharmacokinetics of pentasubstituted pyrrolic Atorvastatin-aminoquinoline hybrid compounds. Acta Trop., v. 242, p. 106924, 2023.
Bezerra, Frank S.; Lanzetti, Manuela; Nesi, Renata T.; Nagato, Akinori C.; e Silva, Cynthia P.; Kennedy-Feitosa, Emanuel; Melo, Adriana C.; Cattani-Cavalieri, Isabella; Porto, Luís C.; Valença, Samuel S.. Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries. Antioxidants, v. 12, p. 548, 2023.
Costa, Caroline M. X.; Aparecida-Silva, Cristiane; Gamba, Luis E. R.; de Melo, thalita N.; Barbosa, Gisele; Junior, Manoel O. M.; de Oliveira, Victoria R. T.; de Amorim, Carolinne S.; Moraes, João A.; Barreiro, Eliezer J.; Lima, Lídia M.. Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues. Pharmaceuticals, v. 16, p. 209, 2023.
Corrêa-Netto, Carlos; Strauch, Marcelo A.; Monteiro-Machado, Marcos; Teixeira-Araújo, Ricardo; Fonseca, Juliana G.; Leitão-Araújo, Moema; Machado-Alves, Maria L.; Sanz, Libia; Calvete, Juan J.; Melo, Paulo de A.; Zingali, Russolina B.. Monoclonal-Based Antivenomics Reveals Conserved Neutralizing Epitopes in Type I PLA2 Molecules from Coral Snakes. Toxins, v. 15, p. 15, 2023.
Fujimaki, Carla M. de O.; de Lima, Cleverton K. F.; Miranda, Ana L. P.; Bernardo, Robson R.; Study of the presence of biphenyl polychlorates in the waters of the Bengalas River, Nova Friburgo, Rio de Janeiro. Journal of Engineering Research, v. 3, p. 2-7, 2023.
Gaspar, Tiago B.; Jesus, Tito T.; Azevedo, Maria T.; Macedo, Sofia; Soares, Mariana A.; Martins, Rui Sousa; Leite, Rúben; Rodrigues, Lia; Rodrigues, Daniela F.; Cardoso, Luís; Borges, Inês; Canberk, Sule; Gärtner, Fátima; Miranda-Alves, Leandro; Lopes, José M.; Soares, Paula; Vinagre, João. Generation of an Obese Diabetic Mouse Model upon Conditional Atrx Disruption. Cancers, v. 15, p. 318, 2023.
Gonsalez, Sabrina R.; Gomes, Dayene S.; de Souza, Alessandro M.; Ferrão, Fernanda M.; Vallotton, Zoe; Gogulamudi, Venkateswara R.; Lowe, Jennifer; Casarini, Dulce E.; Prieto, Minofla C.; Lara, Lucienne S.. The Triad Na+ Activated Na+ Channel (Nax)-Salt Inducible KINASE (SIK) and (Na+ + K+)-ATPase: Targeting the Villains to Treat Salt Resistant and Sensitive Hypertension. Int. J. Mol. Sci., v. 24, p. 7887, 2023.
Guimarães, Celina J.; Carneiro, Teiliane R.; Frederico, Marisa J. S.; de Carvalho, Guilherme G. C.; Little, Matthew; Freire, Valder N.; França, Victor L. B.; do Amaral, Daniel N.; Guedes, Jéssica S.; Barreiro, Eliezer J.; Lima, Lídia M.; Barros-Nepomuceno, Francisco W. A.; Pessoa, Cláudia. Pharmacokinetic Profile Evaluation of Novel Combretastatin Derivative, LASSBio-1920, as a Promising Colorectal Anticancer Agent. Pharmaceuticals, v. 15, p. 1282, 2023.
Guilherme, Rafael F.; Silva, José B. N. F.; Waclawiak, Ingrid; Fraga-Júnior, Vanderlei S.; Nogueira, Thaís O.; Pecli, Cyntia; Araújo-Silva, Carlla A.; Magalhães, Nathália S.; Lemos, Felipe S.; Bulant, Carlos A.; Blanco, Pablo J.; Serra, Rafaela; Svensjö, Erik; Scharfstein, Júlio; Moraes, João A.; Canetti, Cláudio; Benjamim, Claudia F.. Pleiotropic antifibrotic actions of aspirin-triggered resolvin D1 in the lungs. Frontiers in Immunology, v. 14, p. 1, 2023.
Kråkström, Matilda; Dickens, Alex M.; Alves, Marina A.; Forssten, Sofia D.; Ouwehand, Arthur C.; Hyötyläinen, Tuulia; Orešič, Matej; Lamichhane, Santosh. Dynamics of the Lipidome in a Colon Simulator. Metabolites, v. 13, p. 355, 2023.
Leite, Debora I.; Moura, Stefany de C. B.; Dias, Maria da C. A.; Costa, Carolina C. P.; Machado, Gustavo P.; Pimentel, Luiz C. F.; Castelo-Branco, Frederico S.; Moreira, Rui; Bastos, Mônica M.; Boechat, Nubia. A Review of the Development of Multitarget Molecules against HIV-TB Coinfection Pathogens. Molecules, v. 28, p. 3342, 2023.
Lima-Araujo, Carlos F.; Carvalho, Rita de C. C.; Peres, Raiza B.; Fiuza, Ludmila F. de A.; Galvão, Bárbara V. D.; Castelo--Branco, Frederico S.; Bastos, Mônica M.; Boechat, Nubia; Felzenszwalb, Israel; Soeiro, Maria de N. C.. In silico and in vitro assessment of anti-Trypanosoma cruzi efficacy, genotoxicity and pharmacokinetics of pentasubstituted pyrrolic Atorvastatin-aminoquinoline hybrid compounds. Acta. Trop. v. 242, p. 106924, 2023.
Macedo, Sofia; Teixeira, Elisabete; Gaspar, Tiago B.; Boaventura, Paula; Soares, Mariana A.; Miranda-Alves, Leandro; Soares, Paula. Endocrine-disrupting chemicals and endocrine neoplasia: A forty-year systematic review. Environ Res., v. 218, p. 114869, 2023.
Merlo, Eduardo; Zimerman, Jeanini; dos Santos, Flávia C. F.; Zanol, Jordana F.; da Costa, Charles S.; Carneiro, Pedro H.; Miranda-Alves, Leandro; Warner, Genoa R.; Graceli, Jones B.. Subacute and low dose of tributyltin exposure leads to brown adipose abnormalities in male rats. Toxicol Lett., v. 376, p. 26-28, 2023.
Montagnoli, Tadeu L.; De Oliveira, Daniela R.; Fraga, Carlos A. M.. Therapeutic Perspectives on ROCK Inhibition for CerebralCavernous Malformations. Kinases Phosphatases, v. 1, p. 72-96, 2023.
Moreira-Souza, Aline, C. A.; Nanini, Hayandra F.; Rangel, Thuany P.; Da Silva, Sthefani R. B.; Damasceno, Beatriz P.; Ribeiro, Beatriz E.; Cascabulho, Cynthia M.; Thompson, Fabiano; Leal, Camila; Santana, Patrícia T.; Rosas, Siane L. B.; de Andrade, Kívia Q.; Silva, Cláudia l. M.; Vommaro, Rossiane C.; de Souza, Heitor S. P.; Coutinho-Silva, Robson. P2X7 Receptor Modulation of the Gut Microbiota and the Inflammasome Determines the Severity of Toxoplasma gondii-Induced Ileitis. Biomedicines, v. 11, p. 555, 2023.
Peres, Rodrigo A. S.; Silva-Aguiar, Rodrigo P.; Teixeira, Douglas E.; Peruchetti, Diogo B.; Alves, Sarah A. S.; Leal, Anna B. C.; Castro, Guilherme F.; Ribeiro, Natalia B. S.; Guimarães, Fernanda V.; Pinheiro, Ana A. S.; Silva, Patrícia M. R. E.; Martins, Marco A.; Caruso-Neves, Celso. Gold nanoparticles reduce tubule-interstitial injury and proteinuria in a murine model of subclinical acute kidney injury. Biochim Biophys Acta Gen Subj., v. 1867, p. 130414, 2023.
Ribeiro, Bianca C. de S.; Faria, Regina V. de C.; Nogueira, Jeane de S.; Valença, Samuel S.; Chen, Lin; Romana-Souza, Bruna. Olive oil promotes the survival and migration of dermal fibroblasts through Nrf2 pathway activation. Lipids, v. 58, p. 59-68, 2023.
Saramago, Luiz C.; Santana, Marcos V.; Gomes, Bárbara F.; Dantas, Rafael F.; Senger, Mario R.; Borges, Pedro H. O.; Ferreira, Vivian N. dos S.; Rosa, Alice dos S.; Tucci, Amanda R.; Miranda, Milene D.; Lukacik, Petra; Strain-Damerell, Claire; Owen, David; Walsh, Martin A.; Ferreira, Sabrina B.; Silva-Jr, Floriano P.. AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro. J. Chem. Inf. Model., 2023.
Souto, Arthur C.; Tempone, Matheus H.; Golçalves, Lyslie A. C.; Borges-Martins, Vladimir P. P.; Peixoto-Rodrigues, Maria C.; Damascena, Ana C. O.; Ferraz, Gabriel; Manhães, Alex C.; Castro, Newton G.; de Melo, Ricardo A. R.; Ventura, Ana L. M.; Kubrusly, Regina C. C.. NMDA Receptor Activation and Ca2+/PKC Signaling in Nicotine-Induced GABA Transport Shift in Embryonic Chick Retina. Neurochemical Research, v. 48, p. 1, 2023.
Souza, Isis N. O.; Andrade, Brenda S.; Frost, Paula S.; Neris, Romulo L. S.; Gavino-Leopoldino, Daniel; Da Poian, Andrea T.; Assunção-Miranda, Iranaia; Figueiredo, Claudia P.; Clarke, Julia R.; Neves, Gilda A.. Different outcomes of neonatal and adult Zika virus infection on startle reflex and prepulse inhibition in mice. Behav. Brain Res., v. 451, p. 114519.
Teixeira-Alves, Lyzes R.; Nobre, Camila C. G.; Reis, Evelyn M.; Miranda-Alves, Leandro; Junior, Clemilson B.. Bosentan Attenuates Sickle Cell Disease Erythrocyte HbS Polymerization and Impaired Deformability Induced by Endothelin-1. Canadian Journal of Physiology and Pharmacology, 2023.
Teixeira-Cruz, Jhonatha M.; Martins-Ferreia, Jainne; Monteiro-Machado, Marcos; Strauch, Marcelo A.; de Moraes, João A.; Amaral, Luciana S.; Valente, Raphael C.; Melo, Paulo A.; Quintas, Luis E. M.. Heparin prevents the cytotoxic activity of Bothrops jararacussu and Apis mellifera venoms in renal cells. TOXICON, v. 223, p. 107011, 2023.
Zimerman, Jeanini; Niño, Oscar M. S.; da Costa, Charles S.; Zanol, Jordana F.; Comério, Milena; de Souza, Letícia N. da G.; Miranda-Alves, Leandro; Miranda, Rosiane A.; Lisboa, Patrícia C.; Camilo, Tays A.; Rorato, Rodrigo; Alves, Guilherme A.; Frazão, Renata; Zomer, Helena D.; Freitas-Lima, Leandro C.; Graceli, Jones B.. Subacute high-refined carbohydrate diet leads to abnormal reproductive control of the hypothalamic-pituitary axis in female rats. Reproductive Toxicology, v. 119, p. 108410, 2023.
2022
de Almeida, Lana R.; Alves, Marina A.; Mastella, Ana M. O.; Garret, Rafael; Pereira, Maria J. R.. Neotropical mustelids: fecal metabolome diversity and its potential for taxonomic discrimination. Integrative Zoology, 2022.
Amorim, Carolinne S.; Moraes, João A.; Magdalena, Ingrid J.; López, Sheila G.; Carneiro, Ana C. D.; Nunes, Isabelle K. C.; Pizzatti, Luciana; Sardela, Vinícius, F.; Neto, Aquino F. R.; Mirotti, Luciana C.; Pereira, Henrique M. G.; Renovato-Martins, Mariana. Extracellular Vesicles From Stored Red Blood Cells Convey Heme and Induce Spic Expression on Human Monocytes. Frontiers in Immunology, v. 13, p. 1, 2022.
Doi:10.3389/fimmu.2022.833286
Amorim, Carolinne S.; Docasar, Clara L.; Guimarães-Bastos, Daniel; Frony, Ana C.; Barja-Fidalgo, Christina; Renovato-Martins, Mariana; Moraes, João A.. Extracellular Vesicles Derived from MDA-MB-231 Cells Trigger Neutrophils to a Pro-Tumor Profile. Cells, v. 11, p. 1875, 2022.
Doi://doi.org/10.3390/cells11121875
Andrade, Marcelle N.; Melo-Paiva, Francisca; Teixeira, Mariana P.; de Lima-Junior, Nieldson C.; Soares, Paula; Graceli, Jones B.; de Carvalho, Denise P.; Morris, Eduardo A. R.; Ferreira, Andrea C. F.; Miranda-Alves, Leandro. Environmentally relevant dose of the endocrine disruptor tributyltin disturbs redox balance in female thyroid gland. Molecular and Cellular Endocrinology, v. 553, p. 111689, 2022.
Barbosa, G.; Gelves, Luis G. V.; Costa, Caroline M. X.; Franco, Lucas S.; De Lima, João A. L.; Aparecida-Silva, Cristiane; Teixeira, John D.; Mermelstein, Cláudia S.; Barreiro, Eliezer J.; Lima, Lídia M.. Discovery of Putative Dual Inhibitor of Tubulin and EGFR by Phenotypic Approach on LASSBio-1586 Homologs. Pharmaceuticals, v. 15(8), p. 1-22, 2022.
Doi: //doi.org/10.3390/ph15080913
Brasiel, Poliana G. A.; Guimarães, Fernanda V.; e Silva, Patricia M. R.; Bou-Habib, Dumith C.; Carvalho, Vinicius F.. Therapeutic Efficacy of Flavonoids in Allergies: A Systematic Review of Randomized Controlled Trials. Journal of Immunology Research, v. 2022, 2022.
Cardoso, Tassya C.; Rocha, Marianna A.; Monteiro, Matheus M. L. V.; Alves, Vinícius S.; Savio, Luiz E. B.; Silva, Cláudia L. M.. The blockage of downstream P2Y2 receptor signaling inhibits the prostate cancer cell adhesion to endothelial cells. Life Sciences, v. 306(1), p. 120793, 2022.
Doi://doi.org/10.1016/j.lfs.2022.120793
Costa, Bianca; Corrêa, Luana B.; e Silva, Patricia M. R.; de Sá, Yago A. P. J.; Guimarães, Fernanda V.; Alencar, Luciana M. R.; Simões, Rafael L. Helal-Neto, Edward; Ricci-Júnior, Eduardo; Henriques, Maria G. M. O.; Rosas, Elaine C.; Santos-Oliveira, Ralph. Using pure Fucoidan and radiolabeled Fucoidan (99mTc-Fucoidan) as a new agent for inflammation diagnosis and therapy. Food Hydrocolloids for Health, v. 2, p. 10049, 2022.
Caruso, Lucas ; Nadur, N. Fonseca ; Da Fonseca, M. Brandão ; Peixoto, De Almeida, Larissa; Lacerda, R. Barbosa; Graebin, C. Stephan; Kümmerle, Arthur Eugen. The Design of Multi-target Drugs to Treat Cardiovascular Diseases: Two(or more) Birds on One Stone. Current Topics in Medicinal Chemistry, v. 22, p. 366-394, 2022.
Doi:10.2174/1568026622666220201151248
Costa, Tamara G. F.; Oliveira, Marina M.; Toledo, Marina M.; Santos, Helio B.; Thome, Ralph G.; Cortes, Vanessa F.; Santos, Herica L.; Quintas, Luis E. M.; Fontes, Carlos F. L.; Barbosa, Leandro A.. Effect of Fe3+ on Na,K-ATPase: Unexpected activation of ATP hydrolysis. Biochimica et Biophysica Acta (BBA), v. 1864, p. 183868, 2022.
Cunha, Thayssa T. S.; Silva, Rafaela R.; Rodrigues, Daniel A.; Pinheiro, Pedro S. M.; Kronenberger, T.; Sant’Anna, Carlos M. R.; Noël, François. Fraga, Carlos A. M.. Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases. Biomolecules, v. 12(8), p. 1-18, 2022.
Doi://doi.org/10.3390/biom12081112
Dantas, Rafael F.; Torres-Santos, Eduardo; Silva-Júnior, Floriano P.. Past and future of trypanosomatids high-throughput phenotypic screening. Mem Inst Oswaldo Cruz, v. 117, p. e210402, 2022.
Faria, Jessica V.; Passos, Fernanda P.Z.; da Costa, Paulo H.A.; de Oliveira, Andressa P.; Cruz, Yasmin O.D. da; Castelo-Branco, Frederico S.; Lourenço, Maria C.S.; Murta, Silvane M.F.; Junior, Policarpo A.S.; Bernardino, Alice M.R.; Bastos, Monica M.; Boechat, Nubia. Novel 2-Nitroimidazole and Imidazooxazole Derivatives and their Activity against Trypanosoma cruzi and Mycobacterium tuberculosis. Medicinal Chemistry, v. 18, p. 701-709, 2022.
DOI: 10.2174/1573406418666211116144952
de Faria, Rachel A.; Oliveira, Pamella C. O.; de Carvalho, Mariana D. P.; Peixoto, Bruno S.; Severino, Vanessa G. P.; Tinoco, Luzineide W.; Rodrigues, Silvana V.; de Moraes, Marcela C.. High-resolution inhibition profiling and ligand fishing for screening of nucleoside hydrolase ligands in Moringa oleifera Lamarck. Journal of Pharmaceutical and Biomedical Analysis, v. 211, p. 114614, 2022.
DOI: //doi.org/10.1016/j.jpba.2022.114614
França, Patrícia R. C.; Lontra, Anna C. P.; Fernandes, Patricia D.. Endometriosis: A Disease with Few Direct Treatment Options. Molecules, v. 27, p. 4034, 2022.
DOI: 10.3390/molecules27134034
Ferreira, Tatiana P. T.; Guimarães, Fernanda V.; Sá, Yago A. P. J.; Ribeiro, Natalia B. S.; de Arantes, Ana C. S.; Carvalho, Vinicius F.; Sousa, Lirlândia P.; Perretti, Mauro; Martins, Marcos A.; e Silva, Patricia M. R.. Annexin-A1-Derived Peptide Ac2-26 Suppresses Allergic Airway Inflammation and Remodelling in Mice. Cells, v. 11, p. 759, 2022.
Figueiredo-Junior, Alexsandro T.; Valença, Samuel S.; Fintonelli, Priscilla V.; dos Anjos, Francisca F.; de Brito-Gitirana, Lycia; Takiya, Christina M.; de Deus, Manuella L. D.. Treatment with Bixin-Loaded Polymeric Nanoparticles Prevents Cigarette Smoke-Induced Acute Lung Inflammation and Oxidative Stress in Mice. Antioxidants, v. 11, p. 1293, 2022.
Gouvêa, Marcos M.; de Carvalho, Renata C.; Castelo-Branco, Frederico C.; Boechat, Nubia; Netto, Annibal D. P.; Marques, Flávia F. C.. The cleavage kinetics of hydrazide derivatives of isoniazid by HPLC-UV/DAD and its impact on activity against Mycobacterium tuberculosis. Journal of Chromatography B, v. 1188, p. 123080, 2022.
DOI: //doi.org/10.1016/j.jchromb.2021.123080
Lamichhane, Santosh; Sen, Partho; Dickens, Alex M.; Alves, Marina A.; Härkönen, Taina; Honkanen, Jarno; Vatanen, Tommi; Xavier, Ramnik J.; Hyötyläinen, Tuulia; Knip, Mikael; Orešič, Matej. Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes. Cell Reports Medicine, p. 100762, 2022.
DOI: 10.1016/j.xcrm.2022.100762
Lara, Lucienne S.; Gonzalez, Alexis A.; Hennrikus, Mathew T.; Prieto, Minofa C.. Hormone-dependent regulation of renin and effects on prorenin receptor signaling in the collecting duct. Current Hypertens Review, 2022.
DOI: 10.2174/1573402118666220216105357
Leite, Jacqueline A.; Pôças, Elisa; Maia, Gisele S.; Barbosa, Leandro; Quintas, Luis E. M.; Kawamoto, Elisa M.; da Silva, Maria L. C.; Scavone, Cristoforo; de Carvalho, Luciana E. D.. Effect of ouabain on calcium signaling in rodent brain: A systematic review of in vitro studies. Frontiers in Pharmacology, v. 13, p. 916312, 2022.
DOI: //doi.org/10.3389/fphar.2022.916312
Leser, Felipe S.; Fiuza, Diogo N.; Miranda-Alves, Leandro. Importance of students congresses for medical training: A pioneer experience at Federal University of Rio de Janeiro. Revista Brasileira de Educação e Saúde-REBES, v. 11, p. 464-475, 2022.
DOI: 10.18378/rebes.v11i4.8632
Mansoldo, Felipe R. P.; Garrett, Rafael; Cardoso, Veronica S.; Alves, Marina A.; Vermelho, Alane B.. Metabology: Analysis of metabolomics data using community ecology tools. Analytica Chimica Acta, v. 1232, p. 340469, 2022.
DOI: 10.1016/j.aca.2022.340469
Mendes, Ana B. A.; Motta, Nadia A. V.; Lima, Gabriel F.; Autran, Lis J.; Brazão, Stephani C.; Magliano, D'Angelo C.; Sepúlveda-Fragoso, Vinícius; Scaramello, Christiane B. V.; Graceli, Jones B.; Miranda-Alves, Leandro; Brito, Fernanda C. F.. Evaluation of the effects produced by subacute tributyltin administration on vascular reactivity of male wistar rats. Toxicology, v. 465, p. 153067, 2022.
DOI: //doi.org/10.1016/j.tox.2021.153067
Moreira, Lorrane K. S.; Silva, Rafaela R.; da Silva, Dayane M.; Mendes, Mirella A. S.; de Brito, Adriane F.; de Carvalho, Flávio S.; Sanz, Germán; Rodrigues, Marcella F.; da Silva, Artur C. G.; Thomaz, Douglas V.; de Oliveira, Valéria; Vaz, Boniek G.; Lião, Luciano M.; Valadares, Marize C.; Gil, Eric S.; Costa, Elson A.; Noël, François; Menegatti, Ricardo. Anxiolytic- and antidepressant-like effects of new phenylpiperazine derivative LQFM005 and its hydroxylated metabolite in mice. Behavioural Brain Research, v. 417(24), p. 113582, 2022.
DOI: 10.1016/j.bbr.2021.113582
Nunes, Bruno; Pópulo, Helena; Lopes, José M.; Reis, Marta; Nascimento, Gilvan; Nascimento, Ana G.; Fernandes, Janaína; Faria, Manuel; de Carvalho, Denise P.; Soares, Paula; Miranda-Alves, Leaandro. Connexin Expression in Pituitary Adenomas and the Effects of Overexpression of Connexin 43 in Pituitary Tumor Cell Lines. Genes, v. 13, p. 674, 2022.
Oliveira, Andressa; Moura, Stefany; Pimentel, Luiz; Neto, João; Dantas, Rafael; Silva-Júnior, Floriano P.; Bastos, Monica; Boechat, Nubia. New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells. Molecules, v. 27(3), p. 750, 2022.
DOI: 10.3390/molecules27030750
Ortiz, Cindy J. C.; Silva, Matheus F.; Pruccoli, Letizia; Nadur, Nathália F.; De Azevedo, Luciana L.; Kümmerle, Arthur E.; Guedes, Isabella A.; Dardenne, Laurent E.; Coelho, Luiz F. L.; Guimarães, Marcos J.; Da Silva, Fernanda M. R.; Castro, Newton; Gontijo, Vanessa S.; Rojas, Viviana C. T.; De Oliveira, Merelym K.; Vitela, Fabiana C.; Giusti-Paiva, Alexandre; Barbosa, Gisele; Lima, Lídia M.; Pinheiro, Gabriel B.; Veras, Letícia G.; Mortari, Márcia R.; Tarozzi, Andrea; Júnior, Cláudio V.. Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation. RSC Medicinal Chemistry, v. 13, p. 568-584, 2022.
DOI: //doi.org/10.1039/D1MD00374G
Portovedo, Sérgio; Neto, Leonardo V.; Soares, Paula; de Carvalho, Denise P.; Takiya, Christina M.; Miranda-Alves, Leandro. Aggressive nonfunctioning pituitary neuroendocrine tumors. Brain Tumor Pathology, 2022.
DOI: 10.1007/s10014-022-00441-6
de Queiroz, Aline C.; Barbosa, G.; de Oliveira, Victória R. T.; Alves, Hélio M.; Alves, Marina A.; Carregaro, V.; da Silva, João S.; Barreiro, Eliezer J.; Alexandre-Moreira, Magna S.; Lima, Lídia M.. Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity. Plos One, v. 17(6), p. e0269447, 2022.
DOI: 10.1371/journal.pone.0269447
Rodrigues-Pereira, Paula; Andrade, Marcelle N.; Santos-Silva, Ana P.; Teixeira, Mariana P.; Soares, Paula; Graceli, Jones B.; de Carvalho, Denise P.; Dias, Glaecir R. M.; Ferreira, Andrea C. F.; Miranda-Alves, Leandro. Subacute and low-dose tributyltin exposure disturbs the mammalian hypothalamus-pituitary-thyroid axis in a sex-dependent manner. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, v. 254, p. 109279, 2022.
DOI: 10.1016/j.cbpc.2022.109279
Santos, Carine; Pimentel, Luiz; Cazian, Henayle; Oliveira, Andressa; Silva-Júnior, Floriano P.; Dantas, Rafael; Hoelz, Lucas; Marinho, Debora; Cunha, Anna; Bastos, Monica; Boechat, Nubia. Hybrids of Imatinib with Quinoline: Synthesis, Antimyeloproliferative Activity Evaluation, and Molecular Docking. Pharmaceuticals, v.15(3), p. 309, 2022.
DOI: 10.3390/ph15030309
Santos, Stephanie A. C. S.; Persechini, Pedro M.; Henrique-Santos, Bianca M.; Bello-Santos, Victória G.; Castro, Newton C.; de Sousa, Júlia C.; Genta, Fernando A.; Santiago, Marcelo F.; Coutinho-Silva, Robson; Savio, Luiz E. B.; Kurtenbach, Eleonora. P2X7 Receptor Triggers Lysosomal Leakage Through Calcium Mobilization in a Mechanism Dependent on Pannexin-1 Hemichannels. Frontiers in Immunology, v. 13, p. 752105, 2022.
DOI: 10.3389/fimmu.2022.752105
Serra, Magda F.; Cotias, Amanda C.; Pimentel, Andreza S.; de Arantes, Ana C. S.; Pires, Ana L. A.; Lanzetti, Manuella; Hickmann, Jandir M.; Barreto, Emiliano; Carvalho, Vinicius F.; Silva, Patrícia M. R.; Cordeiro, Renato S. B.; Martins, Marco A.. Gold Nanoparticles Inhibit Steroid-Insensitive Asthma in Mice Preserving Histone Deacetylase 2 and NRF2 Pathways. v. 11, p. 1659, 2022.
Silva, Grazielle F.; da Silva, Jaqueline S.; de Alencar, Allan K. N.; da Silva, Marina M. C.; Montagnoli, Tadeu L.; Rocha, Bruna S.; de Freitas, Rosana H. C. N.; Sudo, Roberto T.; Fraga, Carlos A. M.; Zapata-Sudo, Gisele. Novel p38 Mitogen-Activated Protein Kinase Inhibitor Reverses Hypoxia-Induced Pulmonary Arterial Hypertension in Rats. Pharmaceuticals, v.15(7), p. 1-16, 2022.
DOI: 10.3390/ph15070900
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