Artigos em periódicos
2020
Nascimento, M.S.S. ; Câmara, V.R.F. ; Costa, J.S. ; Barbosa, J.M.C. ; Lins, A.S.M. ; Salomão, K. ; Castro, S.L.; Carvalho, S.A. ; Silva, E.F. ; Ferreira. E.; ; Fraga, C.A.M. Identification of novel functionalized carbohydrazonamides designed as Chagas disease drug candidates. Medicinal Chemistry , v. 16, p. 774-783, 2020.
Doi:10.2174/1573406415666190627103013
Araujo-montoya, B.O. ; Senger, M.R. ; Gomes, B.F. ; Harris, G. ; Owens, R.J. ; Silva-jr, F.P. Schistosoma mansoni cathepsin D1: Biochemical and biophysical characterization of the recombinant enzyme expressed in HEK293T cells. Protein Expression and Purification, v. 167, p. 105532, 2020.
Azalim, P. ; Monte, F.M. ; Rendeiro, M. M. ; Liu, X. ; Odoherty, G. A. ; Fontes, C. F. ; Leitão, S. G. ; Quintas, L. E. M. ; Noël, F. Conformational states of the pig kidney Na+/K+-ATPase differently affect bufadienolides and cardenolides: A directed structure-activity and structure-kinetics study. Biochemical Pharmacology , v. 171, p. 113679, 2020.
Doi: 10.1016/j.bcp.2019.113679
Costa, G. ; Montagnoli, T. L. ; Da SILVA, J. S. ; Alencar, A. K. N. ; Gamba, L. E.R. ; Alves, B. E.O. ; Moraes, M. C. ; Trachez, M. M ; Nascimento, J. H.M. ; Coelho, P.M.P. ; Mendez-otero, R. ; Lima, L.M. ; Barreiro, E.J. ; Sudo, Roberto Takashi ; Sudo, G.Z . New benzofuran N-acylhydrazone reduces cardiovascular dysfunction in obese rats by blocking TNF-alpha synthesis. Drug Design Development and Therapy , v. 14, p. 3337-3350, 2020.
Pereira, P.R. ; Macedo, S. ; Gaspar, T. B. ; Canberk, S. ; Selmi-ruby, S. ; Maximo, V. ; Soares, P. ; Alves, L. M. Relevant dose of the environmental contaminant, tributyltin, promotes histomorphological changes in the thyroid gland of male rats. Molecular and Cellular Endocrinology , v. 502, 2020.
Doi: 10.1016/j.mce.2019.110677
3.
Reis, E.M. ; Nobre, C. C. G. ; Chagas, A.P. ; Alves, L.M. ; Junior, C.B . Effects of TSH in Erythrocyte Osmotic Fragility: Signalling Pathway. International Journal of Blood Research and Disorders, v. 7, p. 1-7, 2020.
Doi: 10.23937/2469-5696/1410048
Lindoso, RS ; Lopes, J.A. ; Binato, R. ; Abdelhay, E. ; Takiya, C.M. ; Miranda, K.R. ; Lara, L. S. ; Viola ,A ; Bussolati, B ; Vieyra, A. ; Collino F . Adipose Mesenchymal Cells-Derived EVs Alleviate DOCA-Salt-Induced Hypertension by Promoting Cardio-Renal Protection. Molecular Therapy-Methods & Clinical Development, v. 16, p. 63-77, 2020.
Doi:10.1016/j.omtm.2019.11.002
Dick, C. F. ; Guimarães, L.M. ; Kelly, L.F.C. ; Cortes, A.L. ; Morcillo, L.L.S. ; Sampaio, L.S. ; Fernandes, J. R.M. ; Vieyra, A. . A ferric reductase of Trypanosoma cruzi (TcFR) is involved in iron metabolism in the parasite. Experimental Parasitology, v. 217, p. 107962, 2020.
Doi:10.1016/j.exppara.2020.107962
Lima, J. A. ; R. Costa, T.W. ; Fonseca, A. C.C. ; Amaral, R. F. ; Nascimento, M.D. S.B. ; Filho, O.A.S. ; Miranda, A.L.P. ; Neto, D.C.F.; Lima, F.R.S. ; Hamerski, L. ; Tinoco, L. W. Geissoschizoline, a promising alkaloid for Alzheimer?s disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking. Bioorganic chemistry, v. 104, p. 104215, 2020.
Nunes, I.C.N. ; Souza, E.T. ; Martins, I.R.M. ; Barbosa, G. ; Junior, M.O.N. ; Medeiros, M.M. ; Silva, S. W.D. ; Balliano, T.L.; Silva, B.A. ; Silva, P.M.R.; Carvalho, V.F. ; Martins, M.A.; Lima, L.M. Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 204, p. 112492, 2020.
DOI: 10.1016/j.ejmech.2020.112492
Carvalho, K.I.M. ; Coutinho, D.S. ; Joca, H.C. ; Miranda, A.S. ; Cruz, J.S.; Silva, E.T.; Souza, M.V.N. ; Faria, R.X. ; Silva, P.M.R. ; Costa, J.C.S. ; Martins, M.A . Anti-Bronchospasmodic Effect of JME-173, a Novel Mexiletine Analog Endowed With Highly Attenuated Anesthetic Activity. Frontiers in Pharmacology , v. 11, p. 1159, 2020.
Doi.: 10.3389/fphar.2020.01159
Pinto, D.P. ; Coutinho, D.S. ; Carvalho, K.I.M. ; Ferrero, M. R. ; Silva, L.V. ; Silveira, G.P. E. ; Silva, D. M.; Araújo, J.F.G. ; Silva, A. C.A. ; Pereira, H.M. ; Fonseca, L.B. ; Faria, R.X. ; Souza, M.V.N. ; Silva, E.T.; Filho, O.A.S. ; Costa, J.C. ; Amendoeira, F. C. ; Martins, M.A. Pharmacological profiling of JME-173, a novel mexiletine derivative combining dual anti-inflammatory/anti-spasmodic functions and limited action in Na+ channels. European Journal of Pharmacology. v. 885, p. 173367, 2020.
Doi:10.1016/j.ejphar.2020.173367
Aguiar, R.P.S. ; Peruchetti, D.B. ; Rocco, P.R.M. ; Schmaier, A.H. ; Silva, P.M.R. ; Martins, M.A. ; Carvalho, Vinicius de Frias ; Pinheiro, A.A.S. ; Neves, C.C . Role of the renin angiotensin system in the development of severe COVID-19 in hypertensive patients. AJP: Lung Cellular and Molecular Physiology, v. 000, p. 000, 2020.
Doi:10.1152/ajplung.00286.2020
Mattos, M. S. ; Ferrero, M. R. ; Kraemer, L. ; Lopes, G. A. ; Reis, D. C. ; Oliveira, F. M. ; Cassali, G. D. ; Brandolini, L. ; Allegretti, M. ; Garcia, C. C. ; Martins, M.A. ; Teixeira, M. M. ; Russo, R. C. CXCR1 and CXCR2 inhibition by Ladarixin improves neutrophil-dependent airway inflammation in mice. Frontiers in Immunology , v. 00, p. 000, 2020.
Silva, M.F. ; Lima, E.T. ; Pruccoli, Letizia ; Castro, N. ; Guimarães, M. ; Silva, F. ; Nadur, N.F. ; Azevedo, L. ; Kümmerle, A. ; Guedes, I.; Dardenne, L. ; Gontijo, V. ; Tarozzi, A. ; Viegas, C. Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer?s Disease. Molecules, v. 25, p. 3165, 2020.
Doi: 10.3390/molecules25143165
Prado, V.M. ; Queiroz, T.B.; Sá, P. M. ; Seiceira, R.C. ; Boechat, N. ; Ferreira, F.F . Mechanochemistry for the production of a hybrid salt used in the treatment of malaria. Green Chemistry, v. 22, p. 51-61, 2020.
Rogerio, K.R. ; Graebin, C.S. ; Domingues, L.H.P. ; Oliveira, L.S. ; Silva, V.S.F.; Ribeiro, C.T.D. ; Carvalho, L. J.M. ; Boechat, N. Novel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum. Current topics in Medicinal Chemistry, v. 20, p. 99-110, 2020.
Doi: 10.2174/1568026619666191019100711
Nunes, I. K. C. ; Souza, E. T. ; Martins, I. R. R. ; Barbosa, G. ; Junior, M. O.M ; Medeiros, M. M. ; Silva, S. W. D. ; Balliano, T. L. ; Silva, A. B. ; Silva, P. M. R. ; VF, C. ; Martins, M. A. ; LM, Lima . Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies. European Journal of Medicinal Chemistry, v. 204, p. 112492, 2020.
Doi: 10.1016/j.ejmech.2020.112492
Silva, N. L. C. ; Mota, N A V ; Soares, M. A. ; Araujo OMO ; Espindola, L C P ; Colombo, A P V ; Lopes, R T ; Brito, F.C. F. ; Miranda, A. L. P. ; Tributino, J.L.M . Periodontal status, vascular reactivity, and platelet aggregation changes in rats submittedto hypercholesterolemic diet and periodontitis. Journal of periodontal research, v. 55, p. 453-463, 2020.
Doi: 10.1111/jre.12730
Gomes, A. C. C. ; Soares, Mariana, A. ; Gomes, A. K. C. ; Silva, Natália, L. C. ; Miranda, A. L. P. ; Tributino, J. L. M. ; LUZ, D. A. ; Amorim, GISELE C. ; Simas, N. K. ; KUSTER, R. M. Antinociceptive constituents from Saccharum officinarum L. juice. Natural product research, v. 34, p. 1-5, 2020.
Doi: 10.1080/14786419.2020.1771708
Rodrigues, D.A. ; Guerra, F.S. ; Sagrillo, F.S.. ; Pinheiro, P.S.M. ; Alves, M.A. ; Thota, S. ; Chaves, L.S. ; Santanna, C.M.R. ; Fernandes, P.D. ; Fraga, C.A.M . Design, Synthesis and Pharmacological Evaluation of First-in-Class Multitarget N-Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors. ChemMedChem, v. 15, p. 539-551, 2020.
Fokoue, H. ; Pinheiro, P. ; Fraga, C. ; Santanna, C. Há algo novo no reconhecimento molecular aplicado à química medicinal?. Quimica nova, v. 43, p. 78-89, 2020.
Doi: 10.21577/0100-4042.20170474
Freitas, R.H.C.N. ; Barbosa, J.M.C. ; Bernardino, P. ; Sueth-santiago, V. ; Wardell, S.M.S.V. ; Wardell, J. L. ; Ricardo, D. D.; Melo,T.G. ; Silva,E.F. ; Salomão, K. ; Fraga, C.A.M . Synthesis and trypanocidal activity of novel pyridinyl-1,3,4-thiadiazole derivatives. Biomedicine & pharmacotherapy, v. 127, p. 110162, 2020.
Doi: 10.1016/j.biopha.2020.110162
Neves, B.J. ; Agnes, J.P. ; Gomes, M.N. ; Donza, M.R.H. ; Gonçalves, R.M. ; Delgobo, M. ; Neto, lauro ; Senger, M.R. R.S. ; Junior, F.P.S. ; Ferreira, S.B. ; Filho, A.Z. ; Andrade, C.H . Efficient identification of novel anti-glioma lead compounds by machine learning models. european journal of medicinal chemistry, v. 189, p. 111981, 2020.
Doi: 10.1016/j.ejmech.2019.111981
Neto, L.R.S. ; Filho, J.T.M. ; Neves, B.J. ; Maidana, R.L.B.R. ; Guimarães, A.C.R. ; Furnham, N. ; Andrade, C.H. ; Silva, F.P . In silico strategies to support fragment-to-lead optimization in drug discovery. Frontiers in chemistry, v. 8, p. 1-18, 2020.
françois
Silva, V.D. ; Silva, R.R. ; Neto, J.G. ; Corcuera, B.L. ; Guimaraes, M.Z. ; Noël, F. ; Antonio, C.B. New α-hydroxy-1,2,3-triazoles and 9h-fluorenes-1,2,3-triazoles: synthesis and evaluation as glycine transporter 1 inhibitors. Journal of the brazilian chemical society, v. 31, p. 1258-1269, 2020.
Doi: 10.21577/0103-5053.20200011
Noël, F.; Lima, J. Pharmacological aspects and clues for the rationale use of Chloroquine/Hydroxychloroquine facing the therapeutic challenges of COVID-19 pandemic. Latin American Journal of Clinical Sciences and Medical Technology, v. 2, p. 28-34, 2020.
Bray, M. ; Rayner, C. ; Noël, F. ; Jans, D. ; Wagstaff, K. Ivermectin and COVID-19: a report in Antiviral Research, widespread interest, an FDA warning, two letters to the editor and the authors' responses. ANTIVIRAL RESEARCH, v. 1, p. 104805, 2020.
Doi: 10.1016/j.antiviral.2020.104805
Noël, F. Suggesting Treatments for COVID-19. Beware! Expectations cannot Replace Good Science. Latin American Journal of Clinical Sciences and Medical Technology, v. 2, p. 43-43, 2020.
Marques, A. M. ; Macena, M. V. ; Cardoso, A. R. ; Hammes, C. S. O. ; Pinheiro, F.M.L. ; Castro, N. G. ; Neves, G.A. Effects of combined 5-HT2A and cannabinoid receptor modulation on a schizophrenia-related prepulse inhibition deficit in mice. Psychopharmacology, v. (), p. 1-13, 2020.
Doi: 10.1007/s00213-020-05485-0
Rodrigues, D.A. ; Pinheiro, P.S.M. ; Sagrillo, F.S.; Freitas, M.C.R. ; Alves, M.A. ; Thota, S. ; Tinoco, L.; Magalhães, A. ; Sant'anna, C. ; Fraga, C.A.M . Structure-property relationship studies of 3-acyl-substituted furans: the serendipitous identification and characterization of a new non-classical hydrogen bond donor moiety. New journal of chemistry, v. 44, p. 10994-11005, 2020.
Thompson'souza, G.A. ; Santos, G.M.P. ; Silva, J.C. ; Muniz, V.S. ; Braga, Y.A.V. ; Figueiredo, R.T. ; Melo, R.C.N. ; Santos, A.L.S. ; Pinto, M.R. ; Neves, J.S. Histoplasma capsulatum -induced extracellular dna trap release in human neutrophils. cellular microbiology, v. x, p. x, 2020.
Sisnande, T. ; Lima, C.K. ; Silva, D.C. ; Moulin ,T.B.. ; Leao, N. ; Amaral, M.J. ; Alves, L.M. ; Lima, L.M.T.R. Dietary zinc restriction promotes degeneration of the endocrine pancreas in mice. Biochimica et biophysica acta-molecular basis of disease, v. 1866, p. 165675, 2020.
Doi: 10.1016/j.bbadis.2020.165675
Reis, E.M. ; Nobre, C.C.G. ; Chagas, A.P. ; Alves, L.M. ; Junior, C.B . Effects of tsh in erythrocyte osmotic fragility: signalling pathway. International journal of blood research and disorders, v. 7, p. 1-7, 2020.
Doi: 10.23937/2469-5696/1410048
Podratz, P.L. ; Merlo, E. ; Araujo, J.F.P. ; Ayub, J.G.M. ; Pereira, A.F.Z. ; Lima, L.C.F. ; Costa, M.B.C. ; Alves, L.M. ; Cassa, S.G.S.C. ; Carneiro, M.T.W.D. ; Fillmann, G. ; Graceli, J.B . Disruption of fertility, placenta, pregnancy outcome, and multigenerational inheritance of hepatic steatosis by organotin exposure from contaminated seafood in rats. Science of the total environment, v. 723, p. 138000-xxx, 2020.
Doi: 10.1016/j.scitotenv.2020.138000
Alves, Marina A. ; Queiroz, A.C. ; Leite, A.B. ; Martins, F.T. ; Doriguetto, A.C. ; Barreiro, E. J. ; Moreira, M.S.A. ; Lima, L.M. . Carbamoyl- N -aryl-imine-urea: a new framework to obtain a putative leishmanicidal drug-candidate. RSC Advances, v. 10, p. 12384-12394, 2020.
Casanova,L.M. ; Rodrigues, L.M. ; Aguiar, P.F. ; Tinoco, L.W . An NMR-Based Chemometric Strategy to Identify Leishmania donovani Nucleoside Hydrolase Inhibitors from the Brazilian Tree Ormosia arborea. Journal of natural products, v. 83, p. 243-254, 2020.
Doi: 10.1021/acs.jnatprod.9b00622
Calassara, L.L. ; Pinto, S.C.; Condack, C.P.M. ; Leite, B.F. ; Nery, L.C.E.S. ; Tinoco, L.W.; Aguiar, F.A. ; Leal, I.C.R. ; Martins, S.M. ; Silva, L.L. ; Raimundo, J.M.; Muzitano, M.F . Isolation and characterization of flavonoids from tapirira guianensis leaves with vasodilatory and myeloperoxidase-inhibitory activities. Natural product research, v. 000, p. 1-4, 2020.
Doi: 10.1080/14786419.2020.1784170
Lourenço, E.M.G. ; Fernandes, J.M. ; Carvalho, V.F. ; Grougnet,R. ; Martins, M.A. ; Jordão, A.K. ; Zucolotto, S.M. ; Barbosa, euzébio g. Identification of a selective pde4b inhibitor from bryophyllum pinnatum by target fishing study and in vitro evaluation of quercetin 3-o-α-l-arabinopyranosyl-(1→2)-o-α-l-rhamnopyranoside. Frontiers in pharmacology, v. 10, p. 1-12, 2020.
Ferreira, T.P.T. ; Lima, J.G.M. ; Filho, F.A.F. ; Sá, Y.A.P.J. ; Arantes, A.C.S. ; Guimarães, F.V. ; Carvalho, V. F. ; Hogaboam, C. ; Wallace, J. ; Martins, M.A. ; Silva, P.M.R . Intranasal flunisolide suppresses pathological alterations caused by silica particles in the lungs of mice. Frontiers in endocrinology, v. 11, p. xx, 2020.
Ventura,R.D. ; Chaves, A.S. ; Magalhaes, N.S. ; Gonzalez, F.B. ; Pacini, M.F. ; Perez, A.R. ; Silva, P.M.R. ; Martins, M.A. ; Carvalho, V.F . Activation of pparγ reduces n-acetyl-cysteine -induced hypercorticoidism by down-regulating mc2r expression into adrenal glands. Free radical biology and medicine, v. xx, p. xx, 2020
Doi: 10.1016/j.freeradbiomed.2020.06.008
Marques, A.M. ; Macena, M.V. ; Cardoso, A.R. ; Hammes, C.S.O. ; Pinheiro, F.M.L. ; Castro, N. G. ; Neves, G. A. Effects of combined 5-HT2A and cannabinoid receptor modulation on a schizophrenia-related prepulse inhibition deficit in mice. Psychopharmacology, v. 00, p. 1-13, 2020.
DOI: 10.1007/s00213-020-05485-0
Pimentel, L.C.F.; Cunha, A.C. ; Hoelz, L.C.B. ; Canzian, H.F. ; Marinho, D.I.L.F. ; Boechat,N. ; Bastos, M.M. Phenylamino-pyrimidine (pap) privileged structure: synthesis and medicinal applications. Current topics in medicinal chemistry, v. 20, p. 227-243, 2020.
Doi: 10.2174/1568026620666200124094949
Cordeiro, N.M. ; Freitas, R.H.C.N. ; Fraga, C.A.M. ; Fernandes, P.D . New 2-amino-pyridinyl-n-acylhydrazones: synthesis and identification of their mechanism of anti-inflammatory action. Biomedicine & pharmacotherapy, v. 123, p. 109739, 2020.
Doi: 10.1016/j.biopha.2019.109739
Cordeiro, M.S. ; Simas, D.L.R. ; Sabino, J.F.P. ; Reyes, M.S.M. ; Muñoz-wug, M.A. ; Oliva-hernández, Bessie, E. ; S.;Antônio ,J.R. ; Fernandes, P.D. ; Giorno, T.B.S . Characterization of the antinociceptive activity from stevia serrata cav. Biomedicines, v. 8, p. 79, 2020.
Doi: 10.3390/biomedicines8040079
Salomé, DC ; Cordeiro, N.M. ; Valerio, T.S. ; Santos, D.A. ; Alves, P.B. ; Alviano, C.S. ; Alviano, D.S. ; Fernandes, PD . Aristolochia trilobata: Identification of the Anti- Inflammatory and Antinociceptive Effects. Biomedicines, v. 8, p. 111-129, 2020.
Doi: 10.3390/biomedicines8050111
Sakipova, Z. ; Giorno, T.B.S. ; Bekezhanova, T. ; Wong, N.S.H. ; Shukirbekova, A. ; Fernandes, P.D. ; Boylan, F . Pharmacological Evaluation of Artemisia cina Crude CO2 Subcritical Extract after the Removal of Santonin by Means of High Speed Countercurrent Chromatography. Molecules, v. 25, p. 2728, 2020.
Doi: 10.3390/molecules25122728
Cordeiro, N.M. ; Freitas, R.H.C.N. ; Fraga, C.A.M. ; Fernandes, P.D . Therapeutic effects of anti-inflammatory n-acylhydrazones in the resolution of experimental colitis. Journal of pharmacology and experimental therapeutics, v. 374, p. jpet-ar-2020-000074, 2020.
Tavares, L. P. ; Negreiros-lima, G. ; Lima, K. M. ; E Silva PM ; Pinho, V. ; Teixeira, M. M. ; Souza LP . Blame the signaling: role of cAMP for the resolution of inflammation. Pharmacological research, v. x, p. xx, 2020.
Doi: 10.1016/j.phrs.2020.105030
Souza, B.R. ; Saguie , B.O.; Nogueira , N.P.A.; Paes , M. ; Valença, S.S. ; Atella , G.C. ; Costa, A.M.A. Oleic acid and hydroxytyrosol present in olive oil promote ROS and inflammatory response in normal cultures of murine dermal fibroblasts through the NF-κB and NRF2 pathways. Food research international, v. 131, p. 108984, 2020.
Doi: 10.1016/j.foodres.2020.108984
Alves, D.R.F. ; Pinto, J.B. ; Rodrigues, F.R. ; Valverde, P. ; Fernandes, D.C.S. ; Accioly, M. ; Valenca, S.S. ; Perini, J.A. ; Jorge, R.V . Cox-2 expression in breast cancer and impact on survival outcomes. Journal of cancer science and clinical therapeutics, v. 04, p. 120-132, 2020.
Cattani-cavalieri, I. ; Valença, S.S. ; Schmidt, M . Nanodomains in cardiopulmonary disorders and the impact of air pollution. Biochemical society transactions, v. 05, p. 50, 2020.
Cordeiro, N.M. ; Freitas,R.H.C.N. ; Fraga, C.A.M ; Fernandes, P.D . New 2-amino-pyridinyl-n-acylhydrazones: synthesis and identification of their mechanism of anti-inflammatory action. Biomedicine & pharmacotherapy, v. 123, p. 109739, 2020.
Doi: 10.1016/j.biopha.2019.109739
Montoya, B.O. ; Senger, M.R. ; Gomes, B.F. ; Harris, G. ; Owens, R.J. ; JunioR, F.P.S. Schistosoma mansoni cathepsin d1: biochemical and biophysical characterization of the recombinant enzyme expressed in hek293t cells. Protein expression and purification , v. 167, p. 105532, 2020.
Doi: 10.1016/j.pep.2019.105532
Azalim, P. ; Monte, F.M. ; Rendeiro, M. M. ; Liu, X. ; Odoherty, G. A. ; Fontes, C. F. ; Leitão, S. G. ; Quintas, L. E. M. ; Noël, F.G. . Conformational states of the pig kidney na+/k+-atpase differently affect bufadienolides and cardenolides: a directed structure-activity and structure-kinetics study. Biochemical pharmacology , v. 171, p. 113679, 2020.
Pereira, P.R. ; Macedo, S. ; Gaspar, T. B. ; Canberk, S. ; Ruby, S.S. ; Maximo, V. ; Soares, P. ; Alves, L.M . Relevant dose of the environmental contaminant, tributyltin, promotes histomorphological changes in the thyroid gland of male rats. Molecular and cellular endocrinology , v. 502, p. 110677. 2020.
Prado,V.M.; Queiroz,T.B.; Sá,P.M. ; Seiceira, R.C.; Boechat, N. ; Ferreira,F.F. Mechanochemistry for the production of a hybrid salt used in the treatment of malaria. Green chemistry , v. 22, p. 51-61, 2020.
Rogerio,K.R. ; Graebin, C. S. ; Domingues, L. H. P. ; Oliveira, L. S. ; Silva, V. S. F. ; Ribeiro, D.C. T. ; Carvalho, L. J. M. ; Boechat, N. Novel quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione derivatives against chloroquine-resistant plasmodium falciparum. Current topics in medicinal chemistry , v. 20, p. 99-110, 2020.
Doi: 10.2174/1568026619666191019100711
Marques, A.M., Macena, M.V., Cardoso, A.R. et al. Effects of combined 5-HT2A and cannabinoid receptor modulation on a schizophrenia-related prepulse inhibition deficit in mice. Psychopharmacology 237, 1643–1655 (2020).
Doi: 10.1007/s00213-020-05485-0
2019
Silva, J.S. ; Sun,X. ; Ahmad, S. ; Wang, H. ; Sudo, R.T. ; Varagic,J. ; Ferrario, C.M. ; Sudo, G.Z. ; Groban, L . G-Protein-Coupled-Estrogen agonist g1 improves diastolic function and attenuates cardiac ras activation in estrogen-deficient hypertensive rats. Journal of cardiovascular pharmacology , v. 1, p. 1, 2019.
Doi: 10.1097/fjc.0000000000000721
Felix, N.S. ; Mendonça,L. ; Braga, C.L. ; Silva, J.S. ; Samary, C.S. ; Vieira, J.B. ; Cruz, F. ; Rocha, N.N. ; Sudo, G.Z. ; Rocco, P.R.M. ; Silva, P.L. Effects of infigratinib, new fibroblast growth factor receptor-1 inhibitor, with or without sildenafil in experimental pulmonary arterial hypertension. British journal of pharmacology , v. 1, p. `1, 2019.
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