Permanent Professors
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Professors working in research, education and tutoring students, always in tune with PPGFQM mission, vision and strategic objectives. Professors with academic excellence, leadership, able to qualify highly-skilled human resources, to fundraise, to have international, national and regional visibility, besides contributing to the scientific and technologic production of quality within the Program.
Arthur Eugen Kümmerle
Curriculum: http://lattes.cnpq.br/5598000938584486;
ORCID: //orcid.org/0000-0002-8458-0975
Address: Instituto de Ciências Exatas, Departamento de Química. BR 465, Km 7, Departamento de Química, Instituto de Ciências Exatas Cidade Universitária
Laboratory: Laboratório de Diversidade Molecular e Química Medicinal – LaDMol-QM
Phone number: +55 (21) 26821872
e-mail: akummerle@ufrrj.br
Bio: Associate Professor II at the Federal Rural University of Rio de Janeiro (UFRRJ), where he started in 2010. He holds a degree in Pharmacy from the Federal University of Rio de Janeiro (2003), a Master's degree in Organic Chemistry from the Institute of Chemistry of the Federal University of Rio de Janeiro (2005), and a Ph.D. in Chemistry from the Institute of Chemistry of the Federal University of Rio de Janeiro (2009) with a sandwich period (2006-2007) at the Université de Strasbourg (France). Visiting Professor at the Université de Strasbourg - France (2012), researcher level 2 CNPq (since 2013), Young Scientist of Our State FAPERJ (since 2015), treasurer (2016-2018) vice-director (2018-2020) and current (2020) -2022) Director of the Division of Medicinal Chemistry of the Brazilian Society of Chemistry, Deputy Coordinator (2015-2017) and Coordinator of the Graduate Program in Chemistry at UFRRJ (2017-2019). He has experience in the area of Pharmacy and Organic Chemistry, with an emphasis on Medicinal Chemistry and Synthesis of heterocycle compounds as drug candidates, using microwave synthesis and cross-coupling reactions with metals as tools. He works mainly on the following topics: planning anti-inflammatory and antitumor drugs and treating neurodegenerative diseases such as Alzheimer's. Recently, he has been dedicating himself to obtaining fluorescent compounds with pharmacological properties in order to get theranostic compounds.
Research lines: Development of fluorescence compounds with theranostic applications in Alzheimer's Disease; Planning, Synthesis, and Pharmacological Evaluation of Bioactive compounds with properties on targets linked to Alzheimer's Disease; Use of Microwave Synthesis and cross-coupling with metals in obtaining and derivatizing bioactive compounds; Synthesis and development of new drug candidates.
Ana Luisa Palhares de Miranda
Curriculum: http://lattes.cnpq.br/8705469754628887; https://orcid.org/0000-0002-4410-9521
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco B/ss, sala 22, Cidade Universitária
Laboratory: Laboratory of Experimental Pharmacology Studies (LEFEx)
Telephone: +55 (21) 2562-6503
E-mail: analu@pharma.ufrj.br
Bio: Ana Luísa Palhares de Miranda holds a B.S. in Pharmacy at UFRJ, a Ph.D. in Pharmacology at the Institut National Polytechnique de Toulouse (1986), and conducted post-doctoral research at the Centre de Recherche Sanofi in Toulouse (1988). Currently, she is an Associate Professor IV, Vice-Director, and Associate Director of Graduation Programs at UFRJ Pharmacy School, a member of the Brazilian Society for Pharmacology and Experimental Therapeutics (SBFTE), a member of the Brazilian Society for Chemistry (SBQ), and member of the Brazilian Association of Pharmaceutical Sciences (ABCF). Coordinator at the Laboratory of Experimental Pharmacology Studies (LEFEx), she researches Pharmacology and Development of Drugs with emphasis on the Pharmacology of Inflammation, Pain, and Thrombosis, and in the areas of Biological Assays, Biological Quality Control, collaborating closely with researchers in the area of Medicinal Chemistry and Chemistry of Natural Products, coordinating projects, and tutoring students in different levels—scientific initiation, masters and Ph.D. Works at the Graduate Program in Pharmaceutical Sciences (FF, UFRJ) and the Graduate Program in Pharmacology and Medicinal Chemistry (ICB, UFRJ). She published 69 papers in specialized journals, and more than 150 papers presented in academic events. She possesses 12 registered technological patented products. She participated in more than 30 events in Brazil and abroad. She tutored 16 master’s dissertations and 3 Ph.D. theses, besides having guided 26 scientific initiation research projects in the areas of pharmacology, pharmacy, and chemistry. Some keywords contextualizing her scientific, technological, and artistic/cultural production are: chronic-degenerative inflammatory diseases, pain, anti-inflammatories, painkillers, antithrombotics, and antiplatelet drugs.
Lines of research: Pharmacological Assessment of Bioactive Substances; Biological Assays: research, development, and quality control
Cláudia Lucia Martins da Silva
Grantee: CNPq 1D
Laboratory: Laboratory of Biochemistry and Molecular Pharmacology (LFBM)
Curriculum: http://lattes.cnpq.br/6943489346365796; https://orcid.org/0000-0001-9227-6036
Telephone: +55 (21) 3938-6732
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco J, sala 17. Cidade Universitária
E-mail: silva.claudiamartins.ufrj@gmail.com
Bio: She is a CNPq research productivity fellowship recipient and member of the Deliberative Committee of the Brazilian Society for Pharmacology and Experimental Therapeutics (SBFTE). A pharmacist, she developed her thesis at the Institute of Medical Biochemistry (UFRJ) with an emphasis on vascular pharmacology, having taken her sandwich Ph.D. also at the Université Catholique de Louvain. Her postdoctoral research was conducted at USP in a project about the regulation of endothelial nitrergic via. She is currently an Associate Professor 4 at UFRJ where she develops her Line of Research in the Laboratory of Biochemistry and Molecular Pharmacology (ICB/UFRJ) in experimental models associated with inflammation and hyperplasia, which are general characteristics of two chronic diseases of high prevalence: schistosomiasis and prostatic hyperplasia. On Vascular Pharmacology and Inflammation, she coordinates projects investigating functional alterations of endothelial cells, mononuclear cells, and vascular remodeling caused by schistosomiasis inflammation, with emphasis on the nitrergic via, oxidative stress, and P2 purinergic signaling (Diretório de Pesquisa/CNPq: Biology of the endothelial cell). The basic research project aims at elucidating the physiopathology of schistosomiasis and identifying new targets with translational potential for alternative therapeutics. Another line of research under her coordination studies the participation of adrenoceptors and EGF receptors in the physiopathology of benign prostatic hyperplasia (BPH), and more recently she initiated a project evaluating the interaction between prostatic tumoral cells and endothelial cells. This project has the potential for innovation and development of new drugs. The researcher is affiliated with the Brazilian Society for the Progress of Science (SBPC), SBFTE, the Brazilian Club of Purines, and Graduate Women in Science. Member of the editorial team of Frontiers in Analytical and Experimental Pharmacology Journal, and reviewer at the European Journal of Pharmacology, Journal of Pharmacology and Experimental Therapeutics, and PLoS One. She was the coordinator of the Program of Research in Pharmacology and Inflammation (ICB/UFRJ). She is a supervisor within the Graduate Program in Pharmacology and Medicinal Chemistry (UFRJ) and has already supervised Ph.D. theses in the Graduate Program in Physiology (USP) and Biophysics (UFRJ).
Main projects: 1) Diretório de Pesquisa do CNPq: Biology of the Endothelial Cell; 2) Pharmacological evaluation of new multitarget-directed antagonists of α1-adrenergic receptors and 5-HT1A serotonergic for the treatment of benign prostatic hyperplasia - LDT5 drug candidate; 3) Investigation on the role of transactivation of the EGF receptor by the α1-adrenergic receptor in benign prostatic hyperplasia.; 4) Purinergic and nitrergic signaling in endothelial cells and murine macrophages: relevance in the physiopathology of schistosomiasis; 5) Evaluation of the endothelial oxidative stress in schistosomiasis inflammation; 6) Modulation of purinergic signaling of P2Y1 endothelial receptors for melatonin.
João Alfredo de Moraes Gomes da Silva
Grantee: CNPq 2 and JCNE-FAPERJ
Curriculum: http://lattes.cnpq.br/6043039357110992; https://orcid.org/0000-0002-8563-6432
Laboratory: Laboratory of Redox Biology (Labio RedOx)
Telephone: +55 (21) 3938-6733
Address: Avenida Carlos Chagas Filho, 373. CCS, bloco J, sala 25. Ilha do Fundão
E-mail: joaomoraes@icb.ufrj.br
Bio: Currently, he is a PQ-2 CNPq research productivity fellowship recipient and a FAPERJ "Young Scientist from Our State" grantee. He is the adjunct coordinator in the Research Program in Pharmacology and Inflammation at UFRJ Institute of Biomedical Sciences. He works as Adjunct Professor in the Laboratory of Redox Biology (Labio RedOx), and he is also a technical advisor for the Ministry of Education (INEP). He holds a B.S. in Biological Sciences from UERJ (2005), an M.S. and a Ph.D. both also from UERJ, and both in Biology (Nuclear Biosciences). Part of his doctoral research was conducted at Paris Cardiovascular Research Center (PARCC). Conducted postdoctoral research at the Laboratory of Cellular and Molecular Pharmacology (UERJ), sponsored by FAPERJ postdoctoral fellowship “Grade 10”. He is experienced in the area of Pharmacology, with an emphasis on Biochemical and Molecular Pharmacology, mainly working with: inflammatory mediators, cardiovascular diseases, disintegrins, signaling pathways, and extracellular vesicles.
Main projects: 1) Inflammatory diseases and metabolic disorders: molecular and therapeutic targets; 2) Nrf2 as a therapeutic target for the treatment of obesity and its associated comorbidities; 3) Immunometabolism Network: metabolic approaches for the treatment of chronic inflammatory diseases; 4) New molecular targets and pharmacological prospection of natural products with antifibrotic action; 5) Polarization of neutrophils for the phenotype N1 as a possible strategy for treating cancer; 6) Importance of tumor-derived microvesicles in the polarization of neutrophils in vivo: new therapeutic approaches; 7) Segmentation of vascular and perivascular niches as a regenerative therapy for chronic obstructive pulmonary disease; 8) Studies on the physiopathology of chronic inflammatory diseases prevalent among seniors.
Gilda Angela Neves
Curriculum: http://lattes.cnpq.br/1352255992428449; https://orcid.org/0000-0002-7027-3851
Laboratory: Laboratory of Molecular Pharmacology
Telephone: +55 (21) 2280-4694
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco J, sala 29. Cidade Universitária
E-mail: ganeves@icb.ufrj.br
Bio: She holds a BS in Pharmacy from the Federal University of Rio Grande do Sul (2001), a master’s degree (2003), and a doctor’s degree (2009) from the Graduate Program of Pharmaceutical Sciences from the Federal University Federal of Rio Grande do Sul. She has conducted postdoc research at GraceLab, Department of Neurosciences from the University of Pittsburgh, supervised by Professor Anthony A. Grace. Currently, she supervises master's and Ph.D. degree students within the Graduate Program in Pharmacology and Medicinal Chemistry at UFRJ and Assistant Professor at the Graduate Program in Pharmacology at UFRJ. She is experienced in the areas of Pharmacology and Electrophysiology, with an emphasis in neuropharmacology, she works mainly with the following themes: schizophrenia, depression, behavioral pharmacology, electrophysiology, dopamine, acetylcholine, memory, development of neuroactive drugs (Researcher ID K-7573-2012; ORCID 0000-0002-7027-3851)
Lines of research: Risk factors and new therapeutic approaches to Schizophrenia treatment and other neuropsychiatric diseases
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Gisele Zapata Sudo
Grantee: CNPq 1D and FAPERJ/CNE
Curriculum: http://lattes.cnpq.br/3556763327505751; https://orcid.org/0000-0002-9066-5027
Laboratory: Laboratory of Cardiovascular Pharmacology (LABCardio)
Telephone: +55 (21) 3938-6505
Adderess: Avenida Carlos Chagas Filho, 373. CCS, bloco J, sala 11. Ilha do Fundão
E-mail: gzsudo@oi.com.br
Bio: She holds a Medical degree from Fundação Técnico Educacional Souza Marques Escola de Medicina (1986), an M.S. in Biological Sciences (Pharmacology and Medicinal Chemistry) from UFRJ (1989), a Ph.D. in Biological Sciences (Biophysics) from UFRJ (1994), a postdoctoral researcher at Wake Forest University Bowman Gray School Of Medicine (1996), a postdoctoral researcher at Wake Forest University Bowman Gray School Of Medicine (2000), and postdoctoral researcher at Wake Forest University Bowman Gray School Of Medicine (2015). Nowadays, she is a tenured professor at UFRJ, a member of the editorial team of The Open Natural Products Journal, a reviewer at the European Journal of Medicinal Chemistry, a reviewer at the Molecular and Cellular Biochemistry, a reviewer at the Chemico-Biological Interactions (Print), reviewer the Journal of Biochemical and Molecular Toxicology, a reviewer at the Journal of Pharmacy and Pharmacology, a reviewer at the Journal of Ethnopharmacology, member of the editorial team of the International Journal of Angiology (Print), a reviewer at the Journal of Pharmaceutical Sciences, member of the editorial team of Scientifica, reviewer of the European Journal of Pharmacology, reviewer of the Journal of Cardiovascular Pharmacology, reviewer of the Hypertension, reviewer of CNPq research projects grant committee. Member of CNPq assessor committee, reviewer FAPERJ research projects grant committee, member of FAPERJ assessor committee. She is experienced in the area of Pharmacology, with an emphasis in Cardiorenal Pharmacology. She has mainly worked with the following themes: potassium currents, magnesium, myocyte, E-4031, cadmium, and retification.
Lines of research: Development of New Alternatives in the Treatment of Heart Failure
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Floriano Paes Silva Junior
Grantee: CNPq 2 and FAPERJ/JCNE
Curriculum: http://lattes.cnpq.br/9391830500474290; https://orcid.org/0000-0003-4560-1291
Laboratory: Laboratory of Experimental and Computational Biochemistry of Drugs (LaBECFAr);
Telephone: +55 (21) 3865-8248
Address: Av. Brasil, 4365. Pavilhão Leonidas Deane, sala 309. Manguinhos.
E-mail: floriano@ioc.fiocruz.br
Bio: He holds a B.S. in Pharmacy (Emphasis on Industry) from Fluminense Federal University (2002) and a Ph.D. in Organic Chemistry from the Federal University of Rio de Janeiro (2005). Postdoctoral research at the Department of Biochemistry and Molecular Biology at Oswaldo Cruz Institute, FIOCRUZ (2006). Postdoctoral research at the Department of Molecular Biosciences, University of Kansas (2008). Currently, he is a Tenure Researcher and coordinator of the Laboratory of Experimental and Computational Biochemistry of Drugs at IOC/FIOCRUZ. He is an experienced researcher in the area of Biochemistry, with an emphasis on the Structure and Chemistry of Proteins, working mainly on the following themes: molecular modeling, drug design, High Throughput Screening (HTS), and Structural Molecular Biology. He was the coordinator of the Graduate Program in Computational and Systems Biology at Oswaldo Cruz Institute/FIOCRUZ from June 2010 to November 2013. Tenure professor in the Graduate Program in Cell and Molecular Biology (concept 7 in CAPES rating system) at Oswaldo Cruz Institute, FIOCRUZ. A member of the direction of the Brazilian Association of Bioinformatics and Computational Biology - AB3C (2012-2014). Also an ordinary member of the Brazilian Society of Biochemistry and Molecular Biology. He is a grantee within the Young Scientist from Our State Program (FAPERJ), since 2009. He works in the editorial team of the Computational Chemistry Journal (http://www.scirp.org/journal/cc/). CNPq Lead Researcher in Biomolecular System Structures - GPESB (http://www.ioc.fiocruz.br/gpesb).
Lines of research: Combination of experimental and computational approaches in biochemistry for prospection, optimization, and characterization of the mechanism of action of molecules that are drug candidates for remedying possible considerable risks against the health of the Brazilian population.
Main projects: 1) Discovery and development of drugs against schistosomiasis through the usage of high-content phenotypic screening, computational modeling, and structural molecular biology; 3) Screening, biological characterization, and planning of new cytotoxic molecules for the treatment of cancer; 3) Discovery, biochemical characterization, and planning of new glucosidase inhibitors as drugs for the treatment of diseases, such as Type 2 diabetes.
Josiane Sabbadini Neves
Curriculum: http://lattes.cnpq.br/2155850602268512; https://orcid.org/0000-0002-6645-1715
Laboratory: Laboratory of Immunopharmacology and Inflammation
Telephone: +55 (21) 3938-6460
Address: Avenida Carlos Chagas Filho 373, Centro de Ciências da Saúde. CCS. Bloco F, sala 14. CEP 21941-902
E-mail: jneves@icb.ufrj.br
Bio: She holds a B.S. in Pharmacology from UFRJ (1999), a Ph.D. in Biological Sciences also from UFRJ (2004), and conducted her postdoctoral research at Harvard Medical School (Boston, MA - USA - 2005-2009). She is a member of the Graduate Program in Immunology and Inflammation (IMPPG/UFRJ) Deliberative Commission, since its founding in 2012, also a member of the team of directors of the International Eosinophil Society, since 2015, and FAPERJ “Scientist from Our State” grantee from 2018 to 2021. She was the coordinator of the Graduate Program in Pharmacology (2013-2014). She has got plenty of experience in mechanisms of leukocyte activation and eosinophil inflammatory response involved in allergic and anthelmintic manifestations. Her current research projects are about the studies on expression and functionality of purinergic receptors in the inflammatory response, especially in eosinophil inflammatory response. As part of another line of scientific inquiry, her objective is to characterize the expression and participation of inflammasome proteins in the activation of eosinophils in vitro and in the eosinophil inflammation in vivo. She also works investigating the signaling pathways that set the liberation of DNA traps by human eosinophils. Currently, she is an Associate Professor at UFRJ Institute of Biomedical Sciences.
Lines of research: She has as her main topic of study the mechanism of leukocyte activation in the inflammatory response, researching I) the expression and the functionality of purinergic receptors in the inflammatory response, especially in the case of eosinophil inflammation; II) the characterization of the expression and participation of inflammasome proteins in the activation of eosinophils in vitro and in the eosinophil inflammation in vivo; III) the investigation of the signaling pathways that set the liberation of DNA traps by human eosinophils
Leandro Miranda Alves
Curriculum: http://lattes.cnpq.br/9883547704448526; https://orcid.org/0000-0001-7832-8717
Laboratory: Laboratory of Experimental Endocrinology (LEEx)
Telephone: +55 (21) 3938-6552
Address: Avenida Carlos Chagas Filho, 373. Bloco G, sala G1-060. Cidade Universitária.
E-mail: leandro.alves@icb.ufrj.br
Bio: He holds a B.S. in pharmacy from UFRJ, a Master’s degree in Sciences (Cell Biology) from Fiocruz, a Ph.D. in Sciences (Pharmacology and Medicinal Chemistry) from UFRJ, and developed his postdoctoral research in Neuroendocrinology from Max Plank Institute of Psychiatry. Currently, he is an Associate Professor at the UFRJ Institute of Biomedical Sciences. He is a permanent supervisor in the Graduate Program in Endocrinology at UFRJ Faculty of Medicine and in the Graduate Program in Pharmacology and Medicinal Chemistry at UFRJ Institute of Biomedical Sciences. He is an evaluator at the National Institute of Educational Studies and Research Anísio Teixeira/Ministry of Education, a member of the Brazilian Society of Cell Biology, the Latin American Thyroid Society, and of the European Society of Endocrinology. He is a FAPERJ “Young Scientist from Our State” grant recipient (2014-2017) and a level-2 CNPq research productivity fellowship recipient. He researches mainly: the cell and molecular basis of hipophysarian tumors, and cellular and molecular mechanisms of action of endocrine disruptors.
Lines of research: The cellular and molecular basis of hipophysarian tumors, cell and molecular mechanisms of action of environmental contaminants – endocrine disruptors
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Leonardo Freire de Lima
Curriculum: http://lattes.cnpq.br/9883547704448526; https://orcid.org/0000-0001-7832-8717
Laboratory: Laboratory of Experimental Endocrinology (LEEx)
Telephone: +55 (21) 3938-6552
Address: Avenida Carlos Chagas Filho, 373. Bloco G, sala G1-060. Cidade Universitária.
E-mail: leandro.alves@icb.ufrj.br
Bio: He holds a B.S. in pharmacy from UFRJ, a Master’s degree in Sciences (Cell Biology) from Fiocruz, a Ph.D. in Sciences (Pharmacology and Medicinal Chemistry) from UFRJ, and developed his postdoctoral research in Neuroendocrinology from Max Plank Institute of Psychiatry. Currently, he is an Associate Professor at the UFRJ Institute of Biomedical Sciences. He is a permanent supervisor in the Graduate Program in Endocrinology at UFRJ Faculty of Medicine and in the Graduate Program in Pharmacology and Medicinal Chemistry at UFRJ Institute of Biomedical Sciences. He is an evaluator at the National Institute of Educational Studies and Research Anísio Teixeira/Ministry of Education, a member of the Brazilian Society of Cell Biology, the Latin American Thyroid Society, and of the European Society of Endocrinology. He is a FAPERJ “Young Scientist from Our State” grant recipient (2014-2017) and a level-2 CNPq research productivity fellowship recipient. He researches mainly: the cell and molecular basis of hipophysarian tumors, and cellular and molecular mechanisms of action of endocrine disruptors.
Lines of research: The cellular and molecular basis of hipophysarian tumors, cell and molecular mechanisms of action of environmental contaminants – endocrine disruptors
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Lídia Moreira Lima
Grantee: CNPq 2 and CNE/FAPERJ
Curriculum: http://lattes.cnpq.br/3986190995983234; https://orcid.org/0000-0002-8625-6351
​Telephone: +55 (21) 3938-6503
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, Bloco B, salas B14 - Cidade Universitária
E-mail: lmlima23@gmail.com
Bio: She holds a B.S. in Pharmacy from UFRJ Pharmacy School (1994), a Master’s degree (1997), and a Ph.D., both in Chemistry (Medicinal Chemistry) from UFRJ. She conducted postdoctoral research in Medicinal Chemistry at the University of Navarra (UNAV, Pamplona, Spain). Currently, she is a professor at the UFRJ Institute of Biomedical Sciences. She was SBQ-Rio Regional Secretary (2010-2012) and head of the UFRJ Faculty of Medicine Department of Drugs (2010-2012). She was a grant recipient within FAPERJ's “Young Scientist from Our State” program and scientific superintendent of the National Institute of Science and Technology of Drugs and Medicines (INCT-INOFAR). She was the coordinator of the Program of Research and Development of Drugs at ICB-UFRJ (2014-2016), vice-coordinator at the Graduate Program in Pharmacology and Medicinal Chemistry (PPGFQM; ICB-UFRJ, 2014-2018) and the undergraduate in Pharmacy Adjunct Director (ICB-UFRJ, 2015-2018). She is the elected coordinator of the Graduate Program in Pharmacology and Medicinal Chemistry (ICB-UFRJ). She works at the Laboratory of Evaluation and Synthesis of Bioactive Substances (LASSBio, ICB, UFRJ) in many research projects in the area of Medicinal Chemistry, mainly with the following themes: new anti-inflammatory design and synthesis; new chemotherapeutic drug candidates (emphasis on antichagasic, leishmanicidal, and antineoplastics) and oral hypoglycemic drugs; optimization of lead-compound; study of drug-likeness properties and xenobiotic metabolism.
Lines of research: Design, synthesis, and biologic evaluation of new anticancer drug prototypes, but also antidiabetes, leishmanicidal, and anti-inflammatory drugs. Studies both in silico and in vitro of phases 1 and 2 metabolisms of new drug candidates.
Lucienne da Silva Lara Morcillo
Grantee: CNPq 2
Curriculum: http://lattes.cnpq.br/6071237996317830; https://orcid.org/0000-0002-2204-8799
Laboratory: Laboratory of Renal Pharmacology
Telephone: +55 (21) 3938-6733
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco J, sala 26. Cidade Universitária
E-mail: lucienne.morcillo@gmail.com
Bio: She holds a B.S. in Pharmacy (1999), a Master’s degree in Biological Sciences - Physiology (2000), and a Ph.D. in Biological Sciences - Physiology (2004), all from UFRJ. Currently, she is an Associate Professor at UFRJ Institute of Biomedical Sciences. She was a FAPERJ “Young Scientist from Our State” recipient (2013), and a level-2 CNPq researcher (2013). She is also a member of the American Physiological Society (APS, 2009), an affiliate member of the Brazilian Academy of Sciences (2013), and a member of the Brazilian Society of Nephrology (2014). Lead researcher at the Laboratory of Renal Pharmacology, which was founded on March 2015. She was a visiting professor at Tulane University (2010-2011), lecturing analyses of clinic studies to medical students, and received the Young Investigator prize from the American Physiological Society (2011). She’s got experience in the areas of Physiology and Pharmacology, with an emphasis on the cardiorenal system. Her main research topic has been the phenomena of regulation in the transport of Na+ and Ca2+ in biological membranes in physiological and pathological conditions. More recently, her lab started researching mechanisms associated with endoplasmic reticulum stress related to renal lesions and to intracellular signaling activated by extracellular Na+.
Lines of research: Identification of new drug candidates for the prevention and treatment of renal diseases
Luis Eduardo Menezes Quintas
Grantee: CNPq 2
Curriculum: http://lattes.cnpq.br/9777575655021376; https://orcid.org/0000-0002-0767-1240
Laboratory: Laboratory of Biochemistry and Molecular Pharmacology (LFBM)
Telephone: +55 (21) 3938-6732
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco J, sala 17. Cidade Universitária
E-mail: lquintas@icb.ufrj.br; lquintas@ufrj.br
Bio: He holds a B.S. in Pharmacy (1992), a Master’s degree in Pharmacology and Experimental Therapeutic (1996), and a Ph.D. in Biophysics (2002) all from UFRJ. He took his doctoral internship at the Université Catholique de Louvain (Belgium, 1997) and his postdoctoral research at the University of Toledo/Medical University of Ohio (USA, 2006-2007). He researches in the area of Biochemical and Molecular Pharmacology, coordinating research projects on the regulation of ion-transporting ATPases, in particular the Na/K-ATPase, and the modulation of new intracellular signaling pathways induced by cardiotonic steroids, besides the pharmacological characterization of new drug candidates. He is an Associate Professor in Pharmacology at UFRJ Institute of Biomedical Sciences and a permanent professor in the Graduate Program in Pharmacology and Medicinal Chemistry. He is a member of various scientific journal editorial teams and also a peer reviewer. He is PLOS ONE, academic editor.
Lines of research: Ion transporting and cellular signaling
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Luzineide Wanderley Tinoco
Grantee: CNPq 2
Curriculum: http://lattes.cnpq.br/1183078302328411; https://orcid.org/0000-0002-1299-6242
Laboratory: Laboratory of Analysis of the Development of Enzymatic Inhibitors (LADIE) and Multi-use Laboratory of Nuclear Magnetic Resonance Analysis (LAMAR))
Telephone: +55 (21) 3938-6793
Address: Av. Carlos Chagas Filho, 373 (CCS) – Bloco H, sala H010 (LADIE) e H28 (LAMAR), Cidade Universitária, Rio de Janeiro, RJ, CEP 21941-902.
E-mail: lwtinoco@nppn.ufrj.br; lamar@nppn.ufrj.br
Bio: She holds a B.S. with a Teaching degree in Chemistry from UERJ, and a Master’s, and Ph.D. both in Chemistry in the area of Nuclear Magnetic Resonance from the Brazilian Institute of Military Engineering (IME). She developed her postdoctoral research at UFRJ Institute of Medical Biochemistry in the area of NMR proteins and a senior internship at the University of California in Riverside in the area of metabolomics. She is currently a level-3 Associate Professor at UFRJ and director of the Institute of Research on Natural Products (IPPN). She is a permanent professor of the Graduate Programs in Chemistry of Natural Products (IPPN-UFRJ) and in Pharmacology and Medicinal Chemistry (ICB-UFRJ), and also a member of the Research Program on Development of Drugs (ICB-UFRJ). She was responsible for the installation of the Multi-use Laboratory of Nuclear Magnetic Resonance Analysis (LAMAR) in IPPN, being its coordinator until now. Her research interests consist of the identification, quantification, and structural determination of natural products in vegetal extracts using NMR, studies on intermolecular interactions, and the structural determination of peptides and proteins using NMR. She also coordinates the Laboratory of Analysis of the Development of Enzymatic Inhibitors (LADIE), where research projects on the application of NMR in the studies of intermolecular interactions for the planning of drugs, which includes the quest for inhibitors for plasmin enzymes in Yersinia pestis, nucleoside hydrolases (Leishmania), and acetylcholinesterase. She collaborated with many research groups from UFRJ and other universities from Brazil and abroad, mainly with the groups at the Universidad de la República in Uruguay and at the Universidad Nacional de Colombia.
Lines of research: Structure, Molecular Interaction, and Metabolomic Analysis using Nuclear Magnetic Resonance Analysis
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Marco Aurélio Martins
Grantee: CNPq 1A and FAPERJ/CNE
Curriculum: http://lattes.cnpq.br/8423282472108016; https://orcid.org/0000-0002-4708-5705
Laboratory: Laboratory of Inflammation, IOC/Fiocruz
Telephone: +55 (21) 2562-1358
Address: Avenida Brasil, 4365. Fiocruz. Rio de Janeiro
E-mail: mam2856@gmail.com
Bio: He holds a B.S. in Biological Sciences from the Federal University of Ceará (1981), a Master’s degree in Biology (Nuclear Biosciences) from UERJ (1984), and a Ph.D. in Cellular and Molecular Biology from Fiocruz (1991). He developed his postdoctoral research at the William Harvey Institute (1996-1997) and at the Imperial College (1997-1998), in London. Tenure researcher at Fiocruz and level 1A CNPq researcher. He leads the Laboratory of Inflammation at Fiocruz since 1991. He researches the area of the pharmacology of the inflammatory process, about which he developed prospective and preclinical studies of both natural and synthetic substances for the treatment of pulmonary inflammatory disorders, such as asthma, silicosis, and COPD. He has published 168 papers in indexed journals, supervised 14 Master’s degree dissertations, 15 Ph.D. theses, and 9 postdoctoral research projects. He is the editor in the pharmacology area of the Brazilian Journal of Medical and Biological Research and a member of the editorial team of Frontiers in Pharmacology.
Lines of research: Pharmacology of the inflammatory process with prospective and preclinical studies of both natural and synthetic substances for the treatment of pulmonary inflammatory disorders, such as asthma, silicosis, and chronic obstructive pulmonary disease
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Manuella Lanzetti Daher de Deus
Grantee: CNPq 1A and FAPERJ/CNE
Curriculum: http://lattes.cnpq.br/8423282472108016; https://orcid.org/0000-0002-4708-5705
Laboratory: Laboratory of Inflammation, IOC/Fiocruz
Telephone: +55 (21) 2562-1358
Address: Avenida Brasil, 4365. Fiocruz. Rio de Janeiro
E-mail: mam2856@gmail.com
Bio: He holds a B.S. in Biological Sciences from the Federal University of Ceará (1981), a Master’s degree in Biology (Nuclear Biosciences) from UERJ (1984), and a Ph.D. in Cellular and Molecular Biology from Fiocruz (1991). He developed his postdoctoral research at the William Harvey Institute (1996-1997) and at the Imperial College (1997-1998), in London. Tenure researcher at Fiocruz and level 1A CNPq researcher. He leads the Laboratory of Inflammation at Fiocruz since 1991. He researches the area of the pharmacology of the inflammatory process, about which he developed prospective and preclinical studies of both natural and synthetic substances for the treatment of pulmonary inflammatory disorders, such as asthma, silicosis, and COPD. He has published 168 papers in indexed journals, supervised 14 Master’s degree dissertations, 15 Ph.D. theses, and 9 postdoctoral research projects. He is the editor in the pharmacology area of the Brazilian Journal of Medical and Biological Research and a member of the editorial team of Frontiers in Pharmacology.
Lines of research: Pharmacology of the inflammatory process with prospective and preclinical studies of both natural and synthetic substances for the treatment of pulmonary inflammatory disorders, such as asthma, silicosis, and chronic obstructive pulmonary disease
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Mônica Macedo Bastos
Grantee: CNPq 1A and FAPERJ/CNE
Curriculum: http://lattes.cnpq.br/8423282472108016; https://orcid.org/0000-0002-4708-5705
Laboratory: Laboratory of Inflammation, IOC/Fiocruz
Telephone: +55 (21) 2562-1358
Address: Avenida Brasil, 4365. Fiocruz. Rio de Janeiro
E-mail: mam2856@gmail.com
Bio: He holds a B.S. in Biological Sciences from the Federal University of Ceará (1981), a Master’s degree in Biology (Nuclear Biosciences) from UERJ (1984), and a Ph.D. in Cellular and Molecular Biology from Fiocruz (1991). He developed his postdoctoral research at the William Harvey Institute (1996-1997) and at the Imperial College (1997-1998), in London. Tenure researcher at Fiocruz and level 1A CNPq researcher. He leads the Laboratory of Inflammation at Fiocruz since 1991. He researches the area of the pharmacology of the inflammatory process, about which he developed prospective and preclinical studies of both natural and synthetic substances for the treatment of pulmonary inflammatory disorders, such as asthma, silicosis, and COPD. He has published 168 papers in indexed journals, supervised 14 Master’s degree dissertations, 15 Ph.D. theses, and 9 postdoctoral research projects. He is the editor in the pharmacology area of the Brazilian Journal of Medical and Biological Research and a member of the editorial team of Frontiers in Pharmacology.
Lines of research: Pharmacology of the inflammatory process with prospective and preclinical studies of both natural and synthetic substances for the treatment of pulmonary inflammatory disorders, such as asthma, silicosis, and chronic obstructive pulmonary disease
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Newton Gonçalves de Castro
Grantee: CNPq 2/Faperj-CNE
Curriculum: http://lattes.cnpq.br/0585051132094289; https://orcid.org/0000-0001-9570-7428
Laboratory: Laboratory of Molecular Pharmacology (LFM)
Telephone: +55 (21) 2280-4694
Address: Avenida Carlos Chagas Filho, 373. Bloco J, sala J1-029. Cidade Universitária.
E-mail: ngcastro@farmaco.ufrj.br
Bio: He is an Associate Professor at UFRJ, where he is also the head of the Laboratory of Molecular Pharmacology. He went to Medical School and then took a Master’s degree in Biomedical Engineering (COPPE-UFRJ). His Ph.D. in Biological Sciences (Biophysics) was taken both at UFRJ, as a primary institution, and at the University of Maryland (USA), where he acted as a Postdoctoral Fellow. He’s got experience in the areas of neuroscience, biophysics, and pharmacology, with emphasis on molecular neuropharmacology and electrophysiological methods, with interest in the research of synaptic receptors and ion pathways (nicotinic, GABA, glutamate) and in the development of drugs for neurodegenerative and psychiatric diseases. His list of publications with related quoting statistics can be found here: https://publons.com/researcher/2861749/newton-g-castro/
Lines of research: Molecular, Cellular, and Behavioural Neuropharmacology; Development of Drugs for Neurodegenerative and Psychiatric Diseases of High Prevalence
Núbia Boechat Andrade
Grantee: CNPq 1D and CNE/FAPERJ
Curriculum: http://lattes.cnpq.br/9152983185617827; https://orcid.org/0000-0003-0146-2218
Laboratory: Laboratory of Drug Synthesis Farmanguinhos (LASFAR)
Telephone: +55 (21) 3977-2458
Address: Rua Sizenando Nabuco,100. Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos
E-mail: nboechat@gmail.com
Bio: She is a CNPq research productivity fellowship recipient and a FAPERJ “Scientist from Our State'' grantee. Between 2014 and 2016 she was vice-secretary of the regional division of the Brazilian Society of Chemistry (SBQ-Rio). In 2007 she was deputy municipal secretary of health of the city of Niterói, in the Rio de Janeiro metropolitan area. She holds a B.S. in Pharmacy from UFRJ Pharmacy School, a Master’s degree in organic synthesis from UFRJ Nucleus of Research on Natural Products, a Ph.D. in chemistry from the UFRJ Institute of Chemistry (IQ-UFRJ), with a doctoral stay at the University of York, England. She conducted her postdoctoral research at the London School of Hygiene and Tropical Medicine. She is a permanent supervisor of the Graduation Program in Pharmacology and Medicinal Chemistry (ICB-UFRJ). She is a senior technology technician at Fiocruz, and since 1986 has been working in different positions, including Farmanguinhos executive director. She is currently Farmanguinhos vice-director of education, research, and innovation, coordinating several projects, among them the implementation of the National Reference Center in Drug Synthesis (CRSF), which will be installed in UFRJ Technology Park. She leads one of the most important R&D groups in drug synthesis in the state, aiming at the public production of drugs and medicines. Numerous total synthesis of important pharmaceuticals for public health have been designed in this laboratory while transferring technology to the national pharmaco-chemical industrial sector. In the field of innovation, her main focus is R&D&I on drugs. She is experienced in the chemistry of organofluorines and in the chemistry of heterocycles, with an emphasis on medicinal chemistry. Hundreds of new molecules have been synthesized for neglected diseases, AIDS, and cancer, also generating powerful antimalarials, antimycobacterial, antichagasics, antiretrovirals, and antileukemics. All are described throughout 106 highly-impacting scientific papers and 45 registered patents. During her 33 year-long Fiocruz scientist career, she has devoted herself to increasing patients' access to medication within the Brazilian National Public Health System (SUS).
Lines of research: Planning and synthesis of new organofluorines and heterocyclic substances for neglected diseases, AIDS and cancer
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Patrícia Dias Fernandes
Grantee: CNPq 1D and FAPERJ/CNE
Curriculum: http://lattes.cnpq.br/7880284010144634; https://orcid.org/0000-0001-6870-6745
Laboratory: Laboratory of Pharmacology of Pain and Inflammation (LaFDI)
Telephone: +55 (21) 3938-6442
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco J, sala 10. Cidade Universitária
E-mail: patrícia.dias@icb.ufrj.br; patricia.dias.icbufrj@gmail.com
Bio: She holds a B.S. in Biological Sciences (medical modality, Biomedicine) from UNIRIO (1987), a Master’s degree (1990), and a Ph.D. (1996) in Biological Chemistry, within the Graduate Program in Biological Chemistry (IBQMed) in UFRJ. She conducted her postdoctoral research in immunopharmacology at the University of São Paulo Department of Immunology (ICB, USP), from 2003 to 2005. She is a tenured professor at the Institute of Biomedical Sciences, from UFRJ. She is a CNPq 1D researcher and a FAPERJ “Scientist from Out State” fellowship recipient. She is the lead researcher at the Laboratory of Pharmacology of Pain and Inflammation (LaFDI), where she coordinates a myriad of research efforts on the quest for new drugs originated from natural or synthetic products that can become candidates for pharmaceutical prototypes in preclinical studies in the areas of inflammation, analgesia, and cancer, using for such, models of acute and chronic diseases. She is coordinator of the Graduate Program in Pharmacology and Medicinal Chemistry (ICB/UFRJ), and editor of the Journal of Ethnopharmacology. She has over 90 published papers in indexed journals and 4 registered patents. She has already supervised 20 Master’s degree dissertations, 8 PhD theses, and 5 postdoctoral research projects. The laboratory has experience in preclinical and toxicology assays for the validation of phytotherapics.
Lines of research: Research for new synthetic or natural molecules, with anti-inflammatory/analgesic or antitumoral potential
Patrícia Machado Rodrigues e Silva Martins
Grantee: CNPq 1B and CNE/FAPERJ
Curriculum: http://lattes.cnpq.br/4062327408011994; https://orcid.org/0000-0002-6613-9000
Laboratory: Laboratory of Inflammation
Telephone: +55 (21) 25621333
Address: Avenida Brasil, 4365. Fioruz. Rio de Janeiro
E-mail: patsilva1910@gmail.com
Bio: She holds a B.S. in Biological Sciences from UERJ (1982), a Master’s degree in Biology (nuclear biosciences) from UERJ (1987), and a Ph.D. in Cell and Molecular Biology from Fiocruz (1991), with a sandwich internship conducted at the Unité de Pharmacologie Cellulaire, Institut Pasteur, Paris (1988). She was a postdoctoral researcher at the National Heart & Lung Institute, Imperial College, London (1996-1998). Currently, she is a Fiocruz Researcher of Public Health (Level III) in the institution’s Laboratory of Inflammation. She is also a CNPq 1B researcher and a FAPERJ “Scientist from Our State” grant recipient. She is an ad-hoc consultant for national and international funding agencies, currently a member of the CNPq CA-BF, and a FAPERJ Area Coordinator. She coordinates the Technical Chamber of Teaching (Câmara Técnica de Ensino do IOC) (2013 - 2017). She is a member of many scientific societies such as the Brazilian Society for the Progress of Science, a member of the board of the Brazilian Society of Pharmacology and Experimental Therapeutics, and a Fellowship of the British Pharmacological Society. She participated in the project TIMER from the European Union. She is an invited reviewer of many scientific publications and a member of the editorial teams of Fibrogenesis and Tissue Repair and of The British Journal of Pharmacology. She published around 148 papers in indexed journals and 7 book chapters. She supervised 30 Master’s degree dissertations, 16 Ph.D. theses, and 10 postdoctoral projects, besides more than 50 undergraduate students having been tutored within the scientific initiation program. She is experienced in the area of pharmacology, with emphasis on Biochemical and Molecular Pharmacology, working mainly with the inflammatory component of chronic pulmonary diseases, both of immunological kind and otherwise, aiming at the identification of new therapies focused on controlling these physiopathologies.
Lines of research: Development of new drugs and identification of new therapeutic targets of interest in the pharmacological control over chronic pulmonary inflammatory diseases, such as asthma, emphysema, and silicosis
Paulo de Assis Melo
Grantee: CNPq 1C and FAPERJ/CNE
Curriculum: http://lattes.cnpq.br/6954875796234519; https://orcid.org/0000-0003-1250-6933
Laboratory: Laboratory of Pharmacology of Toxins
Telephone: +55 (21) 3938-6443
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco J, sala 16. Cidade Universitária
E-mail: melo.pa@gmail.com
Bio: He holds a Medical degree from the Medical School of Campos (1976), his medical residency was in Anesthesiology at UERJ (1978), Specialization (1978), Master’s degree in Pharmacology and Experimental Therapeutics from UFRJ (1983), a Ph.D. in Biological Sciences with emphasis on Biophysics from UFRJ (1992), and postdoctoral research with CNPq scholarship in Oklahoma State University, OK, USA (1995-1996). Tenure professor at UFRJ - Campus of Macaé, CNPq “IC” researcher, and FAPERJ “Scientist from Our State” grant recipient. He has experience in Clinical Anesthesiology, Intensive Therapy, and teaching of Physiology & Pharmacology. He works both in undergraduate and in the Graduation Program in Pharmacology and Medicinal Chemistry. His research projects are mainly about: development of new drugs and experimental models (Pancreatitis), venom pharmacology (toxinology), studies of toxin antagonists in animals and plants; use of natural cytotoxic polycations coming from venom for the development of drugs and newly-designed anticytotoxic substances; investigation on the natural and synthetic polyanions; substances present in plants or synthetic derivatives with anticytotoxic properties and enzyme inhibitors.
Lines of research: Experimental Acute Pancreatitis and agents and/or therapeutic substances and pharmacology of toxins and antagonist substances - pharmacology and toxinology
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Samuel dos Santos Valença
Grantee: 1D CNPQ and CNE/FAPERJ
Curriculum: http://lattes.cnpq.br/3979148859159035; https://orcid.org/0000-0002-1868-9905
Laboratory: Laboratory of Redox Biology
Telephone: +55 (21) 3938-6733
Address: Avenida Carlos Chagas Filho, 373. Prédio do CCS, bloco J, sala 25, Cidade Universitária
E-mail: samuelv@icb.ufrj.br
Bio: He holds a B.S. in Physiotherapy from the University Gama Filho (1997-2000), an M.S. in Morphology from UERJ (2001-2002), and a Ph.D. from the University of Utah (2013-2014). He is currently an associate professor at UFRJ, participating actively in the Graduate Program in Histology and in the Research Program on Pharmacology and Inflammation from the Institute of Biomedical Sciences. He is a technical advisor to the Ministry of Education (INEP). He has experience in topics related to oxidative stress, inflammation, tissue repair, and extracellular matrix.
Lines of research: 1) Chronic Degenerative Pulmonary Diseases having as base-mechanisms inflammation, oxidative stress, and repair; 2) Study, characterization, and development of natural and/or pharmacological therapeutic approaches to face cancer, and pulmonary and metabolic diseases
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